A combined atomic force microscopy and computational approach for the structural elucidation of breitfussin A and B: highly modified halogenated dipeptides from Thuiaria breitfussi.
نویسندگان
چکیده
ACombined Atomic Force Microscopy and Computational Approach for the Structural Elucidation of Breitfussin A and B: Highly Modified Halogenated Dipeptides from Thuiaria breitfussi** Kine Ø. Hanssen, Bruno Schuler, Antony J. Williams, Taye B. Demissie, Espen Hansen, Jeanette H. Andersen, Johan Svenson, Kirill Blinov, Michal Repisky, Fabian Mohn, Gerhard Meyer, John-Sigurd Svendsen, Kenneth Ruud, Mikhail Elyashberg, Leo Gross, Marcel Jaspars,* and Johan Isaksson*
منابع مشابه
Synthesis of Breitfussin B by Late-Stage Bromination.
The breitfussins are halogenated natural products whose structures were determined with the assistance of atomic-force microscopy. The site selectivity of N-bromosuccinimide-mediated bromination of a model breitfussin core was found to be strongly dependent on solvent selection; use of acetone led to oxazole bromination, and use of a pyridine-containing mixture led to pyrrole bromination. This ...
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ورودعنوان ژورنال:
- Angewandte Chemie
دوره 51 49 شماره
صفحات -
تاریخ انتشار 2012